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Draw the structure of phosphatidylserine in the ionic form it would have at pH 7.

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For this structure, see Fig. 1...

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What is the effect of a double bond on fatty acid structure?

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Most double bonds in fatty aci...

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Which of the following is true of sphingolipids?


A) Cerebrosides and gangliosides are sphingolipids.
B) Phosphatidylcholine is a typical sphingolipid.
C) They always contain glycerol and fatty acids.
D) They contain two esterified fatty acids.
E) They may be charged,but are never amphipathic.

F) B) and D)
G) B) and E)

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A

What is the most significant chemical difference between triacylglycerols and glycerophospholipids that leads to their different functions?

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Triacylglycerols are nonpolar hydrophobi...

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Which of the following statements about membrane lipids is true?


A) Glycerophospholipids are found only in the membranes of plant cells.
B) Glycerophospholipids contain fatty acids linked to glycerol through amide bonds.
C) Lecithin (phosphatidylcholine) ,which is used as an emulsifier in margarine and chocolate,is a sphingolipid.
D) Some sphingolipids include oligosaccharides in their structure.
E) Triacylglycerols are the principal components of erythrocyte membranes.

F) B) and E)
G) A) and B)

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Which of the following is not true of sterols?


A) Cholesterol is a sterol that is commonly found in mammals.
B) Sterols are commonly found in bacterial membranes.
C) Sterols are more common in plasma membranes than in intracellular membranes (mitochondria,lysosomes,etc. ) .
D) Serols are precursors of steroid hormones.
E) Sterols have a structure that includes four fused rings.

F) A) and B)
G) B) and E)

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Describe the differences between the glycosphingolipids corresponding to the A,B,and O human blood group antigens.

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The type O structure is found in all three glycosphingolipids.In both type A and type B,there is an added sugar;this sugar differs between type A and B.

Which vitamin is derived from cholesterol?


A) A
B) B12
C) D
D) E
E) K

F) B) and D)
G) B) and E)

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Identify the molecule(s) derived from sterols.


A) Arachidonic acid
B) Gangliosides
C) Phosphatidylglycerol
D) Prostaglandins
E) Cortisol

F) B) and D)
G) All of the above

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Which of the following statements concerning fatty acids is correct?


A) A fatty acid is the precursor of prostaglandins.
B) Phosphatidic acid is a common fatty acid.
C) Fatty acids all contain one or more double bonds.
D) Fatty acids are a constituent of sterols.
E) Fatty acids are strongly hydrophilic.

F) C) and D)
G) A) and E)

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A compound containing N-acetylneuraminic acid (sialic acid) is:


A) cardiolipin.
B) ganglioside GM2.
C) phosphatidylcholine.
D) platelet-activating factor.
E) sphingomyelin.

F) A) and B)
G) A) and C)

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Which of the following best describes the cholesterol molecule?


A) Amphipathic
B) Nonpolar,charged
C) Nonpolar,uncharged
D) Polar,charged
E) Polar,uncharged

F) A) and E)
G) A) and B)

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Tay-Sachs disease is the result of a genetic defect in the metabolism of:


A) gangliosides.
B) phosphatidyl ethanolamine.
C) sterols.
D) triacylglycerols.
E) vitamin D.

F) A) and B)
G) C) and D)

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What are the chemical components of a biological wax,and what is their general structure?

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A wax consists of a long-chain...

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If beeswax,cholesterol,and phosphatidylglycerol were dissolved in chloroform,then subjected to thin-layer chromatography on silica gel using a mixture of chloroform/methanol/water as the developing solvent,which would move fastest?

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In this chromatography, the least polar ...

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Match each of these vitamins with its biological role:

Premises
blood clotting
Ca2+ and phosphate metabolism
vision
prevention of oxidative damage
Responses
Vitamin D
Vitamin K
Vitamin A
Vitamin E

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blood clotting
Ca2+ and phosphate metabolism
vision
prevention of oxidative damage

Explain the cause of hereditary diseases of sphingolipid metabolism,such as Tay-Sachs and Niemann-Pick diseases.

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These diseases are the result of mutatio...

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Which of the following answers is not true?


A) Phospholipase A1 hydrolyzes the fatty acid from the 1-position on the glycerol backbone.
B) Phospholipase B1 hydrolyzes the fatty acid from the 2-position on the glycerol backbone.
C) Phospholipase C hydrolyzes the complete phospho-head group from the glycerol backbone.
D) Phospholipase D hydrolyzes just the head group from the phospho-glycerol backbone.

E) All of the above
F) B) and D)

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What do all these compounds have in common: vitamin A,vitamin K,ubiquinone,and dolichol?

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They are all lipids with potent biological activities derived from isoprenoid precursors.

Match the compounds on the left with the important roles they play listed on the right. (Answers are used only once.)

Premises
important component of myelin membranes
mediates pain and inflammation
necessary for sight
intra-tissue messengers
blood clotting
reducing agent
Responses
thromboxanes
vitamin A
sphingolipids
vitamin E
steroids
prostaglandins

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important component of myelin membranes
mediates pain and inflammation
necessary for sight
intra-tissue messengers
blood clotting
reducing agent

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